Nihonbashi ClinicGIP/GLP-1 Receptor Agonist｜Zepbound Injection
Zepbound Online Consultation
Weekly injection for weight management. GIP / GLP-1 treatment for eligible patients.
English phone consultation · 2.5 mg · 4 pens
Total: ¥24,000 (tax included)
Medicine ¥24,000 + handling ¥0 + consultation ¥0 with purchase + standard delivery ¥0 under the current shipping offer.
Refrigerated delivery within Japan. Prescription follows a medical assessment.
All doses, prices & fee conditionsOnce-weekly self-injection to support weight management
- Nationwide delivery to your home
- Fully online flow through to prescription
- Once-weekly subcutaneous injection (2.5 → 5 → 7.5 → 10 → 12.5 → 15 mg, stepwise titration)
- Alcohol swabs included / +2,000 JPY handling if purchasing only 1 pen
For this self-pay weight-management service, the consultation fee and standard shipping fee are 0 JPY. A 2,000 JPY handling fee applies when ordering only one Mounjaro or Zepbound pen; it is waived when another medicine is included in the same order. Medicine costs are separate. If you choose not to purchase or decline the prescription after completing the consultation, a 3,000 JPY consultation fee applies. No consultation fee is charged if a medical assessment of the questionnaire means the consultation is not performed. See the relevant medicine page for current prices.
Book your consultation in English
- Use the WEB booking page to choose an available appointment. Make a separate reservation for each patient.
- For a first appointment, attach an image of your identification document, such as a passport, and complete the online medical questionnaire as instructed.
- Register a reachable phone number and let us know that you would like the consultation in English.
- The doctor assesses whether treatment or a prescription is appropriate. Payment follows the consultation.
The clinic calls the phone number you register. Consultations are available in English and Japanese. If you are visiting from overseas and cannot receive calls from a Japanese phone number, contact us in advance to arrange a LINE call as an alternative.
Contact official LINE if you need help completing the booking form. Use WEB booking for a medical appointment. Use official LINE for questions before a weight-management appointment or help with the booking process. A LINE message alone does not book a consultation.
[Doctor’s Overview] What is “Zepbound”?
Zepbound (tirzepatide) is a dual agonist acting on both GLP-1 and GIP receptors. Used once weekly, it supports appetite control and post-meal glucose regulation, enabling sustainable weight management. Treatment starts at 2.5 mg and is escalated stepwise depending on tolerability. Always follow your physician’s instructions.
Targets GLP-1/GIP to naturally curb intake and improve glycemic control.
Use on the same weekday; easy to fit into busy schedules.
2.5 → 15 mg, adjusted with attention to GI symptoms and your profile.
Consultation & shipping are free. Nationwide delivery after payment.
Process to online prescription
Book a phone consultation and check available appointments online. Delivery is available within Japan.
How to use (follow your doctor’s instructions)
Remove from the refrigerator; check appearance and expiry. Clean the abdomen, thigh, or upper arm; rotate sites each time.
Press the pen vertically and inject as instructed. Keep pressed for a few seconds after the signal.
Start at 2.5 mg; escalate stepwise per tolerability. If GI symptoms are significant, consult your physician for adjustments.
Watch for nausea, vomiting, diarrhea/constipation, or abdominal pain. If severe symptoms occur, stop and seek care.
* Always follow your physician’s instructions and the official package insert.
Medical information checked: 12 October 2026. Japanese prescribing information (PMDA). Follow the prescription and instructions for your exact product.
Pricing
Your total = medicine price + applicable handling fee. Prices include tax. Consultation with a medicine purchase is ¥0. Standard refrigerated shipping is currently ¥0 (the usual cool-courier charge is ¥2,000).
When ordering only one Zepbound pen, add ¥2,000 handling. This fee is waived if another medicine is included in the same order; that medicine is charged separately. Orders of 2 or more pens have no single-pen handling fee.
Completed consultation without a purchase / prescription declined: ¥3,000 consultation fee. If questionnaire assessment results in no consultation being performed: ¥0 consultation fee.
* Prices/stock may change. Please confirm in the online intake form.
Combination therapy (when appropriate)
Your physician may suggest add-ons based on your profile. Examples that can be synergistic:
Aim: Increase urinary glucose excretion to reduce net calories.
Best for: Frequent snacks / limited time to exercise.
Aim: Temper appetite impulses and support adherence.
Best for: Evening overeating / compulsive snacking.
Aim: Reduce hepatic gluconeogenesis and improve insulin resistance.
Best for: Higher fasting glucose / weight-neutral preference.
Aim: Support bowel movement and fluid balance—useful for constipation/edema patterns.
Best for: Constipation / edema / diet reset.
FAQ
Can I get Zepbound via online consultation?
How much does it cost?
When will it arrive?
Any storage tips?
Can I inject straight from the fridge?
Side effects?
Do I need a Japanese address or residence card?
Can I use a foreign credit card?
Can you ship to my hotel or Airbnb?
Can I consult before arriving in Japan?
I do not have a Japanese phone number. How can I have the consultation?
Can my family or friend in Japan receive the delivery on my behalf?
Can I get an English Doctor Letter for customs?
Can I order several months of supply at once?
Can I use this during pregnancy or breastfeeding?
What should I do if I miss a dose?
What if side effects are strong?
How is Zepbound different from Mounjaro?
How does Zepbound compare to Wegovy?
What is the dose titration schedule?
How soon will I see results?
About the Medicine We Prescribe (Zepbound)
Zepbound (tirzepatide) was PMDA-approved in Japan for obesity treatment in December 2024. Prescribed as self-pay treatment.
We use Eli Lilly Japan products obtained through licensed Japanese pharmaceutical wholesalers only. No personal imports or overseas sources.
Wegovy (semaglutide, 2023 approval for obesity), Mounjaro (tirzepatide, 2023 approval for type-2 diabetes).
FDA-approved (Nov 2023, US) for chronic weight management. Common side effects: nausea, diarrhea, vomiting, constipation, decreased appetite. Rare: pancreatitis, gallbladder disease.
Eligibility for Japan’s Adverse Drug Reaction Relief System depends on appropriate use and the circumstances of the adverse reaction, not simply on self-pay status. Off-label use may fall outside the scheme; PMDA assesses individual cases.
Generic name: Tirzepatide / Class: GIP/GLP-1 receptor agonist / Form: Prefilled pen (single-dose) / Doses: 2.5/5/7.5/10/12.5/15 mg / YJ code (2.5 mg): 2499422G7022. Refer to package insert for full information.
How Zepbound Works
Zepbound is a once-weekly injectable medicine for obesity treatment. Its active ingredient, tirzepatide, is a dual GIP/GLP-1 receptor agonist that acts on both GIP and GLP-1 receptors. It was PMDA-approved in December 2024 for obesity treatment in Japan.
Reference: Jastreboff AM et al. Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1). N Engl J Med 2022.