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Zepbound (Tirzepatide) | Online Prescription | 2.5 mg from 6,000 JPY per pen | Consultation & Shipping Free
GIP/GLP-1 Receptor Agonist｜Zepbound Injection
Zepbound (Tirzepatide)｜Online Prescription｜2.5 mg from 6,000 JPY per pen｜Consultation & Shipping Free
Once-weekly self-injection to support weight management
Consultation Free
Shipping Free
Credit card / Bank transfer
Available via Online Consultation
Home Delivery (after consultation)
LINE Support Available
- Nationwide delivery to your home
- Fully online flow through to prescription
- Once-weekly subcutaneous injection (2.5 → 5 → 7.5 → 10 → 12.5 → 15 mg, stepwise titration)
- Alcohol swabs included / +2,000 JPY handling if purchasing only 1 pen
[Doctor’s Overview] What is “Zepbound”?
Zepbound (tirzepatide) is a dual agonist acting on both GLP-1 and GIP receptors. Used once weekly, it supports appetite control and post-meal glucose regulation, enabling sustainable weight management. Treatment starts at 2.5 mg and is escalated stepwise depending on tolerability. Always follow your physician’s instructions.
Dual pathways
Targets GLP-1/GIP to naturally curb intake and improve glycemic control.
Once-weekly dosing
Use on the same weekday; easy to fit into busy schedules.
Stepwise titration
2.5 → 15 mg, adjusted with attention to GI symptoms and your profile.
Fully online + delivery
Consultation & shipping are free. Nationwide delivery after payment.
Process to online prescription
Three simple steps on your phone. Same-day consults available; nationwide delivery.
1
Online booking
Book 24/7 and complete a short intake form.
~3 min2
Teleconsult (phone)
A physician reviews your history & co-meds to guide dose and cautions.
~2–5 min3
Payment & delivery
We ship after payment. Discreet packaging available on request.
Ships in ~2–3 business daysHow to use (follow your doctor’s instructions)
1Prepare
Remove from the refrigerator; check appearance and expiry. Clean the abdomen, thigh, or upper arm; rotate sites each time.
2Inject
Press the pen vertically and inject as instructed. Keep pressed for a few seconds after the signal.
3Titrate
Start at 2.5 mg; escalate stepwise per tolerability. If GI symptoms are significant, consult your physician for adjustments.
4Monitor
Watch for nausea, vomiting, diarrhea/constipation, or abdominal pain. If severe symptoms occur, stop and seek care.
* Always follow your physician’s instructions and the official package insert.
Pricing
Consultation & shipping: 0 JPY (+2,000 JPY handling if purchasing only 1 pen)
2.5 mg:
24,000 JPY (4 pens)(incl. tax)6,000 JPY / pen
5.0 mg:
40,000 JPY (4 pens)(incl. tax)10,000 JPY / pen
7.5 mg:
56,000 JPY (4 pens)(incl. tax)14,000 JPY / pen
10 mg:
66,000 JPY (4 pens)(incl. tax)16,500 JPY / pen
12.5 mg:
78,000 JPY (4 pens)(incl. tax)19,500 JPY / pen
15 mg:
91,000 JPY (4 pens)(incl. tax)22,750 JPY / pen
VISAMastercardJCBAMEXBank Transfer
* Prices/stock may change. Please confirm in the online intake form.
Combination therapy (when appropriate)
Your physician may suggest add-ons based on your profile. Examples that can be synergistic:
Lusefi (SGLT2 inhibitor)
Aim: Increase urinary glucose excretion to reduce net calories.
Best for: Frequent snacks / limited time to exercise.
Sanorex (appetite suppressant)
Aim: Temper appetite impulses and support adherence.
Best for: Evening overeating / compulsive snacking.
Metformin (biguanide)
Aim: Reduce hepatic gluconeogenesis and improve insulin resistance.
Best for: Higher fasting glucose / weight-neutral preference.
Bofutsushosan (Kampo)
Aim: Support bowel movement and fluid balance—useful for constipation/edema patterns.
Best for: Constipation / edema / diet reset.
FAQ
Can I get Zepbound via online consultation?
Yes. We provide private-care prescriptions for weight management after physician review. Disclose comorbidities and co-meds during the consult.
How much does it cost?
See the price list above. Consultation & standard shipping are free. A +2,000 JPY handling fee applies to single-pen purchases.
When will it arrive?
Typically ships within 2–3 business days after consultation and payment.
Any storage tips?
Store refrigerated at 2–8°C. Keep in the original carton to protect from light. If needed, unopened pens may be kept at room temperature (≤30°C) for up to 21 days. Do not freeze.
Can I inject straight from the fridge?
You can, but letting the pen warm slightly toward room temperature (15–30 min) may reduce injection discomfort. Do not use external heat sources.
Side effects?
Nausea, vomiting, diarrhea/constipation, abdominal pain, and injection-site reactions may occur. If severe symptoms occur, stop and seek medical care.
Do I need a Japanese address or residence card?
No. Hotel, Airbnb, or short-term rental addresses are accepted. Please provide check-in date, hotel/room name, and phone number when ordering. A Japanese residence card is not required.
Can I use a foreign credit card?
Yes. We accept VISA, Mastercard, JCB, and American Express from any country. Notify your bank in advance if international purchases are blocked. Bank transfer is also available for larger orders.
Can you ship to my hotel or Airbnb?
Yes. Please share your check-in date, hotel/accommodation name, and room number in advance. We time the cold-chain delivery to arrive during your stay. Front desk signature required for refrigerated items.
Can I consult before arriving in Japan?
Yes. Phone consultations are available while you are still abroad. Complete the consultation and payment before your trip, and we will time the shipment to arrive at your address in Japan (hotel, Airbnb, etc.) during your stay. We recommend booking at least 7 business days before your desired delivery date.
I do not have a Japanese phone number. How can I have the consultation?
We can conduct the consultation via LINE call, international phone, or your hotel phone. Please let us know your preferred method when booking.
Can my family or friend in Japan receive the delivery on my behalf?
Yes. You can specify any Japan address as the delivery destination, including a family member home, a friend home, or a workplace. Please provide the delivery address and the recipient name when ordering.
Can I get an English Doctor Letter for customs?
The printed medical receipt sent with your medicine can serve as a Doctor Letter free of charge. A formal English letter (with doctor name and prescription details) is available at ¥5,000. Please request when booking or during consultation.
Can I order several months of supply at once?
Yes, as long as the medicine can be used within its expiration date. Up to about 1 year of supply is a general guideline. Our doctor will confirm medical appropriateness during the consultation.
Can I use this during pregnancy or breastfeeding?
Use during pregnancy or breastfeeding is generally not recommended. If you are planning pregnancy or become aware of pregnancy, stop using and consult a doctor. Animal studies have reported effects on fetal development.
What should I do if I miss a dose?
If you notice within 48 hours (2 days) of your scheduled dose, take it as soon as possible and resume the regular weekly schedule. If more than 48 hours have passed, skip that dose and resume the regular schedule from the next scheduled date. Do NOT take two doses at once.
What if side effects are strong?
Nausea is more common at initiation and during dose increases. Drinking water frequently and avoiding fatty foods can help. Most patients adapt within 1-2 weeks. If symptoms are severe, we can slow the titration pace or reduce the dose. Please discuss with the doctor at consultation.
How is Zepbound different from Mounjaro?
Both contain tirzepatide (identical active ingredient) but have different approved indications. Zepbound: FDA/PMDA-approved for obesity treatment. Mounjaro: approved for type-2 diabetes. In Japan, Zepbound (Dec 2024 approval) is prescribed for weight loss, while Mounjaro is often used off-label for diabetes patients also seeking weight management.
How does Zepbound compare to Wegovy?
Zepbound (tirzepatide): dual GIP/GLP-1 action, up to 20% weight loss in SURMOUNT-1 trial. Wegovy (semaglutide): GLP-1 only, 15% in STEP-1. Head-to-head data suggests Zepbound produces greater weight loss on average. Choice depends on tolerability and individual response.
What is the dose titration schedule?
Start at 2.5 mg for 4 weeks, then increase by 2.5 mg every 4 weeks as tolerated. Maintenance doses: 5, 10, or 15 mg weekly. Higher doses generally provide more weight loss but may increase side effects.
How soon will I see results?
Many patients notice appetite reduction within the first few weeks. The SURMOUNT-1 trial reported approximately 20% weight loss at 72 weeks with the 15 mg dose. Gradual results over the 20-week titration period; continued use maximizes effect.
About the Medicine We Prescribe (Zepbound)
Regulatory Status
Zepbound (tirzepatide) was PMDA-approved in Japan for obesity treatment in December 2024. Prescribed as self-pay treatment.
Sourcing
We use Eli Lilly Japan products obtained through licensed Japanese pharmaceutical wholesalers only. No personal imports or overseas sources.
Similar Approved Medicines
Wegovy (semaglutide, 2023 approval for obesity), Mounjaro (tirzepatide, 2023 approval for type-2 diabetes).
International Status & Safety
FDA-approved (Nov 2023, US) for chronic weight management. Common side effects: nausea, diarrhea, vomiting, constipation, decreased appetite. Rare: pancreatitis, gallbladder disease.
Adverse Reaction Relief System
Self-pay usage is NOT covered by Japan Adverse Drug Reaction Relief System.
Details for Pharmacists
Generic name: Tirzepatide / Class: GIP/GLP-1 receptor agonist / Form: Prefilled pen (single-dose) / Doses: 2.5/5/7.5/10/12.5/15 mg / YJ code: 2499420G1027. Refer to package insert for full information.
How Zepbound Works
Zepbound is a once-weekly injectable medicine for obesity treatment. Its active ingredient, tirzepatide, is a dual GIP/GLP-1 receptor agonist that provides stronger weight loss effect than GLP-1 alone. It was PMDA-approved in December 2024 for obesity treatment in Japan.
-20% body weight
Average weight loss at 72 weeks in SURMOUNT-1 trial (15 mg dose).
Once-weekly injection
Subcutaneous injection. Rotate sites weekly.
Dual GIP/GLP-1 action
Activates both GIP and GLP-1 receptors for enhanced metabolic effects.
Gradual titration
2.5 to 15 mg over 20 weeks to minimize side effects.
Reference: Jastreboff AM et al. Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1). N Engl J Med 2022.